Hebbian theory

Hebbian theory describes a basic mechanism for synaptic plasticity wherein an increase in synaptic efficacy arises from the presynaptic cell's repeated and persistent stimulation of the postsynaptic cell. Introduced by Donald Hebb in 1949, it is also called Hebb's rule, Hebb's postulate, and cell assembly theory, and states:

Let us assume that the persistence or repetition of a reverberatory activity (or "trace") tends to induce lasting cellular changes that add to its stability.… When an axon of cell A is near enough to excite a cell B and repeatedly or persistently takes part in firing it, some growth process or metabolic change takes place in one or both cells such that A's efficiency, as one of the cells firing B, is increased.

The theory is often summarized as "Cells that fire together, wire together." It attempts to explain "associative learning", in which simultaneous activation of cells leads to pronounced increases in synaptic strength between those cells. Such learning is known as Hebbian learning.