Neuroinformatics

 

Neuroinformatics is the field that combines informatics and neuroscience. Neuroinformatics is related with neuroscience data and information processing by artificial neural networks. There are three main directions where neuroinformatics has to be applied:

• the development of computational models of the nervous system and neural processes.
• the development of tools for analyzing and modeling neuroscience data,
• the development of tools and databases for management and sharing of neuroscience data at all levels of analysis

 

Hebbian theory

Hebbian theory describes a basic mechanism for synaptic plasticity wherein an increase in synaptic efficacy arises from the presynaptic cell's repeated and persistent stimulation of the postsynaptic cell. Introduced by Donald Hebb in 1949, it is also called Hebb's rule, Hebb's postulate, and cell assembly theory, and states:

Let us assume that the persistence or repetition of a reverberatory activity (or "trace") tends to induce lasting cellular changes that add to its stability.… When an axon of cell A is near enough to excite a cell B and repeatedly or persistently takes part in firing it, some growth process or metabolic change takes place in one or both cells such that A's efficiency, as one of the cells firing B, is increased.

The theory is often summarized as "Cells that fire together, wire together." It attempts to explain "associative learning", in which simultaneous activation of cells leads to pronounced increases in synaptic strength between those cells. Such learning is known as Hebbian learning.

amygdala

The amygdalae (Latin, also corpus amygdaloideum, singular amygdala, from Greek αμυγδαλή, amygdalē, 'almond', 'tonsil', listed in the Gray's Anatomy as the nucleus amygdalæ) are almond-shaped groups of nuclei located deep within the medial temporal lobes of the brain in complex vertebrates, including humans. Shown in research to perform a primary role in the processing and memory of emotional reactions, the amygdalae are considered part of the limbic system.